N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide.It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. Other uses are as extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.
Liu, X.; Yin, H.; Zhang, Z.; Diao, B.; Li, J. Functionalization of lignin through ATRP grafting of poly (2-dimethylaminoethyl methacrylate) for gene delivery. Colloids Surf., B 2015, 125, 230-237.
Zhai, L.; Mun, S.; Gao, X.; Kim, J. W.; Kim, J. Cellulose electro-active paper fabricated by facile solvent exchange pretreatment and its physical and electromechanical properties. Cellulose 2015, 22 (2), 927-933.
危险说明(欧盟):H227-H312+H332-H319-H360D
Combustible liquid. Harmful in contact with skin. Harmful if inhaled. Causes serious eye irritation. May damage the unborn child.
防范说明:P201-P202-P210-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P363-P370+P378q-P501c-X
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant
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